Table 4 Manually verified relationships in the validation and test set with ensemble prediction standard deviation less than interaction-wise threshold and predicted confidence greater than interaction-wise threshold, taking the precision to 100.0
PubMed | Phrases describing relationships in the abstract | Label | Prediction |
|---|---|---|---|
Validation | |||
12150926 | mTOR (P42345)-catalyzed phosphorylation of 4EBP1 (Q13541) in vitro | phosphorylation | phosphorylation |
15733869 | SGK (O00141) physically associates with CREB (P16220) and SGK (O00141) phosphorylates it on serine 133 | phosphorylation | phosphorylation |
15557335 | Src (P12931) phosphorylated Alix (Q8WUM4) at a C-terminal | phosphorylation | phosphorylation |
15527798 | Phosphorylation of MDM2 (Q00987) by the protein kinase AKT (P31749) | phosphorylation | phosphorylation |
10864201 | Radiation-induced phosphorylation of p53 (P04637) protein at serine 15, largely mediated by ATM (Q13315) kinase | Phosphorylation | phosphorylation |
24548923 | Akt (P31749)-mediated phosphorylation of Carma1 (Q9BXL7) | phosphorylation | phosphorylation |
19407811 | BubR1 (O60566) forms a complex with PCAF (Q92831) and is acetylated at lysine 250 | acetylation | acetylation |
Test | |||
21920476 | coilin (P38432) is phosphorylated in Ser184 by both VRK1 (Q99986) | phosphorylation | phosphorylation |
19424295 | Previous studies of cofilin (P23528) have shown that it is phosphorylated primarily by the LIM domain kinases Limk1 (P53667) | phosphorylation | phosphorylation |
22726438 | FGFR2 (P21802) phosphorylates tyrosine residues on Grb2 (P62993) | phosphorylation | phosphorylation |
11154276 | Akt (P31749) decreased ASK1 (Q99683) kinase activity stimulated by both oxidative stress and overexpression in 293 cells by phosphorylating a consensus Akt (P31749) site at serine 83 of ASK1 (Q99683) | phosphorylation | phosphorylation |
25605758 | Phosphorylation of Rab5b (P61020) by LRRK2 (Q5S007) also exhibited | phosphorylation | phosphorylation |
20856200 | Binding of AKT (P31749) (tail region) to Vim (P08670) (head region) results in Vim (P08670) Ser39 phosphorylation | phosphorylation | phosphorylation |
21986944 | MAK (P20794) associates with CDH1 (P12830) (FZR1 (Q9UM11), fizzy/cell division cycle 20 related 1) and phosphorylates CDH1 (P12830) | Negative | phosphorylation |
15862297 | HDM2 (Q00987) phosphorylation by Chk2 (O96017) doubles in the presence of p53 (P04637) | Negative | phosphorylation |
21887822 | Hsp70 (P34932) is phosphorylated by Plk1 (P53350) | Negative | phosphorylation |