Fig. 3
From: Prioritising positively selected variants in whole-genome sequencing data using FineMAV
Annotated screenshot of the bigWig files of the genome-wide FineMAV scores. A FineMAV scores for Han Chinese (90HC, orange), Singaporean Indian (SSIP, blue) and Singaporean Malay (SSMP, grey) populations displayed on the Integrative Genomics Viewer (IGV). The genomic regions on display are the autosomal and the X chromosomes and the horizontal line depicts the 99th percentile. B A multi-locus view of two regions where the left panel displays a locus with a well-known positively selected missense variant in EDAR (rs3827760) in East Asians that also stands out in the SSMP population. The right panel displays a novel locus with two high scoring variants in SSIP: rs151233, a synonymous variant in APOBR and rs151234, an intronic variant in CLN3 that stand out in the SSIP