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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Non-parametric synergy modeling of chemical compounds with Gaussian processes

Fig. 1

Dose–response curves for the Greco data using the squared exponential kernel (top row, a, b), the logarithmic squared exponential kernel (second from top, c, d), the Hill curve (third from top, e, f) and the MuSyC model (bottom row, g, h). For both GPs with different kernels and for the MuSyC model we fit the complete dose–response surface, and plot monotherapeutic slices. Left side: results for drug 1, right side: results for drug 2. Results from both GP regressions are plotted on their natural scale: as (linear) \(x_i/l_i\) for the squared exponential kernel and as \(\log (x_i/l_i+1)\) for the logarithmic squared exponential kernel. Note the difference in the estimates of the uncertainty

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