Fig. 19
From: Non-parametric synergy modeling of chemical compounds with Gaussian processes
Illustration of the Hand model. In this case doses \(x_{1}\) and \(x_{2}\) are split into \(N_1=N_2=3\) parts and the partitions are applied sequentially. The application of the first two partitions \(x_{1}^{1}\) and \(x_{2}^{1}\) is guided by the arrows 1-9, after that the process continues in the same way until all partitions of both drugs are applied. The partitions of the drug 1 are illustrated in orange and the partitions of the drug 2 are illustrated in blue