Skip to main content
Fig. 4 | BMC Bioinformatics

Fig. 4

From: AttCRISPR: a spacetime interpretable model for prediction of sgRNA on-target activity

Fig. 4

Preference for each position-dependent nucleotide on the sgRNA sequence. a–c Bars show the score of preference after standardization, and the higher the number, the more positive it is for the activity of sgRNA. The numbers below indicated the position of the nucleotides on-target DNA. d–f Preference surfaces for each position-dependent nucleotide fitted with Bézier surfaces. Each position-dependent nucleotide is a control point. The coordinates of the control points on the vertical axis represent the degree of preference, and the higher the position-dependent nucleotide corresponding to the control point is, the more positive it is for the activity of sgRNA. The contour plots at the bottom show the area of position-dependent nucleotides which have different contributions to the activity of sgRNA.

Back to article page