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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Comparative analysis of aneurysm subtypes associated genes based on protein–protein interaction network

Fig. 1

Overview of data source and network-based proximity between aneurysm subtypes. a Bar plot shows the number of genes associated with each aneurysm subtype recorded in the AGD database. The color of the bar corresponds to whether the genes could be found in the background PPI network or not. b Box plot presenting the SAB level between one aneurysm subtype and all other studied subtypes. The middle line of each box represents the corresponding median SAB value. c Scattered box plot describing the SAB value between AAA (left) or TAA (right) and all other studied subtypes. Each dot represents one aneurysm subtype. The names of corresponding aneurysm subtypes are labeled. d Heatmap describing the PPI network-based proximity (i.e. SAB values) between different aneurysm subtypes. The exact SAB values are also shown on each corresponding cell. AGD, the Aneurysm Gene Database; PPI, protein–protein interaction; AAA, abdominal aortic aneurysm; TAA, thoracic aortic aneurysm; TAAD, thoracic aortic aneurysm and dissection; AA, aortic aneurysm; AD, aortic dissection; ASH, aneurysmal subarachnoid hemorrhage; CA, cerebral aneurysm

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