Fig. 1
From: M2PP: a novel computational model for predicting drug-targeted pathogenic proteins
The framework of M2PP. a Construct the target set, disease set and drug set; b Construct heterogeneous networks: the target-disease association network, target-drug interaction network, disease-drug association network, disease-disease similarity network, target-target similarity network and drug-drug topological structure similarity network; c Construct features for target-disease pairs; d Train the random forest model and predict association scores for unconfirmed target-disease pairs