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Table 4 Successfully predicted target-disease associations on the whole network in top 10

From: M2PP: a novel computational model for predicting drug-targeted pathogenic proteins

Target name

Disease name

Have CDs

Rank

Evidence

ALOX5

Breast cancer

Yes

1

[45]

NQO1

Lung cancer

Yes

2

[94]

MMP14

Non-small-cell lung cancer

Yes

3

[95, 96]

BRAF

Breast cancer

Yes

5

[97]

ERBB2

Colon cancer

Yes

6

[98, 99]

MMP14

Stomach cancer

Yes

8

[100]

ERBB2

Hepatocellular Cancer

Yes

10

[101, 102]

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BMC Bioinformatics

ISSN: 1471-2105

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