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Table 5 Top DR-related gene candidates

From: Machine learning-based predictions of dietary restriction associations across ageing-related genes

Joint rank

Gene

Normalised DR-probability

Ranking

Mean score

{GO terms, BRF}

{PathDIP, CAT}

{GO terms, BRF}

{PathDIP, CAT}

1

GOT2

0.861

0.840

0.882

5th

6th

2

GOT1

0.853

0.946

0.760

2th

35th

3

TSC1

0.847

0.714

0.979

19th

1th

4

CTH

0.846

0.764

0.928

11th

3th

5

GCLM

0.823

0.700

0.946

23th

2th

6

IRS2

0.801

0.826

0.777

8th

31th

7

SESN2

0.801

1

0.602

1th

80th

  1. Top DR-related gene candidates jointly defined by the two strongest models. Top-association ranking is provided relative to the number of common \(Ageing_{NotDR}\)-related genes