Fig. 4

Performance comparison of the original model implemented in programming language R, the original model in C, and the extended model implemented in C. The x-axis shows the simulated treatment length in hours. The y-axis shows the runtime in seconds to complete the simulation. Each experiment (i.e., test case 2 with different simulated treatment lengths (i.e., 15 min, 1 h, 12 h, and 24 h)) is run at least three times and their error bars represent runtime variability. The model-parameter values of experiments are from Table 2. The resulting graph shows that the computational performance of the model is improved significantly in the C environment. The extended model in C environment has the shortest computation time