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Table 2 Model-parameter values of the three test cases used for model validation and performance analysis

From: vCOMBAT: a novel tool to create and visualize a computational model of bacterial antibiotic target-binding

Parameter Testcase 1 Testcase 2 Testcase 3
Starting population \(1e^{6}\) \(1e^{6}\) \(1e^{6}\)
Initial antibiotic level (mol/cell) \(1e^{3}\) \(1e^{3}\) \(1e^{6}\)
Simulated treatment length (s) 86400 86400 86400
Target molecules 100 100 100
Maximum kill rate 0 0.001 0.001
Killing threshold 50 60 60
Replication threshold 50 50 50
Maximum replication rate 0 0.00025 0.00025
Binding rate 1 1 1
Unbinding rate 0.01 0.01 0.01
Drug Molecular Weight 555.5 555.5 555.5
Carrying capacity \(1e^{9}\) \(1e^{9}\) \(1e^{9}\)
Intracellular volume \(1e^{-15}\) \(1e^{-15}\) \(1e^{-15}\)