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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Periodic synchronization of isolated network elements facilitates simulating and inferring gene regulatory networks including stochastic molecular kinetics

Fig. 5

CaiNet recovers noise-induced bi-stability and oscillations. a Sketch of a positive autoregulatory feedback motive combined with enzyme-mediated degradation. b Left panel: comparison of a CaiNet simulation of the positive autoregulatory feedback motive according to scenario 2 (blue line) and scenario 3 (red line) with a Gillespie simulation (yellow line). Right panel: histogram of respective gene product levels. c Sketch of a negative autoregulatory feedback motive combined with enzyme-mediated degradation. d Left panel: comparison of a CaiNet simulation of the negative autoregulatory feedback motive according to scenario 2 (blue line) and scenario 3 (red line) with a Gillespie simulation (yellow line). Right panel: Fourier transformation of the time traces in the left panel

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BMC Bioinformatics

ISSN: 1471-2105

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