Fig. 9

AUROCs of differential methylation calls. Accuracy in determining differential methylation was measured by generating datasets consisting of two groups (A and B) with varying \(\Delta \theta\) (\(\theta _A\) and \(\theta _B\) levels are shown in top panels and when one or two of three replicates have low \(\text{BS}_{\rm eff}\) (‘GGB’ and ‘GBB’, respectively.) For ‘GBB’ (top box) and ‘GGB’ (bottom box) \(N_{\rm{BS}} = 10\) and \(N_{\rm{BS}} = 6\), respectively, for each technical replicate. X-axis shows whether HMC or ADVI was used to evaluate or approximate the posteriors