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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Topology preserving stratification of tissue neoplasticity using Deep Neural Maps and microRNA signatures

Fig. 1

Sunburst diagram depicting sample ontology. The outermost layer represents the neoplasticity status, and the innermost the tissue-of-origin. In the labels, + represents neoplastic tissue, and - represents non-neoplastic tissue. Wedge size is proportional to the number of samples (shown in brackets). Eight class labels [Bronchus and lung (62), Endocrine RS (57), Adrenal gland (20), Intestine (20), Lymph node (18), Testis (15), Small intestine (11), and Paraganglion (10)] are omitted due to small wedge size. In total, there are 22 unique classes of combined tissue-of-origin and neoplasticity as shown in the outer ring. Only 5 tissues-of-origin contain both neoplastic and non-neoplastic samples (CSO Soft tissues, Breast, Skin, Pancreas, and Bronchus and Lung). CSO Soft tissues Connective, subcutaneous, and other soft tissues, Endocrine RS endocrine glands and related structures, Heart MP heart, mediastinum, and pleura, Hematopoietic RS hematopoietic and reticuloendothelial system

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