Fig. 3
From: CROPSR: an automated platform for complex genome-wide CRISPR gRNA design and validation
Comparison of the scoring performance of CROPSR with the Chopchop algorithm. A Density plot of the score generated by the Chopchop scoring algorithm against the “gene % rank”, a ranking of experimentally-determined relative performance of gRNAs on a per-gene basis. B Density plot of the CROPSR scoring algorithm against the gene % rank. C Binned scatter + box plot of the Chopchop scoring algorithm against the gene % rank. The gRNA targeted for experimental use by Chopchop are those in the 80–100% bin. D Binned scatter + box plot of the CROPSR scoring algorithm against the gene % rank