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Table 3 Study parameters for the third simulation scenario resulting in 20 settings in total

From: Evaluation of tree-based statistical learning methods for constructing genetic risk scores

Parameter

Considered realizations

Odds ratio of GxE interaction

1.2, 1.5, 1.8, 2.1, 2.4

Amount of noise SNPs

45

Interacting GxE SNP j

2, 5

Correlation between \(E_1\) and \(E_2\)

0.5, 0.9

Sample size

2000

Prevalence

Resulting in balanced data sets

MAF

Randomly chosen from [0.15, 0.45]

Repetitions

100