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Table 2 Mean values of 1000 estimates, with corresponding standard deviations, obtained under the constraint \(\uplambda _2 \ge \uplambda _1\). On/off-seq-2 process with true parameter values: \(q_{\text {on}} = 0.1, q_{\text {off}} = 0.2, \uplambda _1 = 2, \uplambda _2 = 1\)

From: Statistical inference for a quasi birth–death model of RNA transcription

  \(\varvec{q}_{\textbf{on}}\) \(\varvec{q}_{\textbf{off}}\) \({\boldsymbol{\uplambda}}_1\) \({\boldsymbol{\uplambda}}_2\)
Mean 0.1066 0.1911 1.9910 1.0004
SD 0.0036 0.0096 0.0960 0.0278