Table 2 Mean values of 1000 estimates, with corresponding standard deviations, obtained under the constraint \(\uplambda _2 \ge \uplambda _1\). On/off-seq-2 process with true parameter values: \(q_{\text {on}} = 0.1, q_{\text {off}} = 0.2, \uplambda _1 = 2, \uplambda _2 = 1\)

From: Statistical inference for a quasi birth–death model of RNA transcription