Fig. 2

Pentad accurately calculates averaged compartments and detects their dynamics. A Cis-pentads for mouse cells with conditional knock-out (KO) of cohesin loading factor (NIPBL; data from Schwarzer et al. [18]). B Cis-pentads for human cells with knock-out (KO) of cohesin releasing factor (WAPL; data from Haarhuis et al. [17]). Quantification of compartment strength for different types of compartment interactions is shown to the right with box plots. **, P-value ≤ 0.01; ***, P-value ≤ 0.001; ****, P-value ≤ 0.0001, Wilcoxon signed-rank test