Fig. 2
From: Computationally repurposing drugs for breast cancer subtypes using a network-based approach
Schematic view of the proposed framework for identification of best pair of repurposing drugs for each breast cancer subtype. METABRIC dataset is used to obtain copy number aberration and gene expression data for breast cancer subtypes. HapMap data is used to obtain copy number variation information. Lincs dataset is used to obtain the effect of different drug compounds on gene expression of cancer samples. KEGG dataset is used to create a universal pathway network [44]. And finally, DrugBank’s drug interference checker is used to check any possible interference between each pair of drugs