Computationally repurposing drugs for breast cancer subtypes using a network-based approach

BMC Bioinformatics

Table 5 Top 20 drugs corresponding to subtype 4

Rank	Drug	Dosage (μm)	Treatment time (h)	Score	Drug type	References
1	Rupatadine	0.04	24	− 0.58	Approved
2	Ribavirin	10	24	− 0.52	Approved	[65]
3	Palbociclib	0.04	24	− 0.5	Approved	[98]
4	Raclopride	10	24	− 0.48	Investigational
5	PHA-793887	10	24	− 0.47	Investigational
6	Bafilomycin A1	0.05	6	− 0.46	Experimental
7	Raloxifene	0.04	24	− 0.46	Approved	[99]
8	EDTA	0.04	24	− 0.46	Approved	[93]
9	Maraviroc	10	24	− 0.46	Approved	[64]
10	Ebselen	10	24	− 0.45	Investigational	[100]
11	Dasatinib	10	24	− 0.45	Approved	[101]
12	Labetalol	0.04	24	− 0.45	Approved
13	Amiprilose	0.04	24	− 0.44	Experimental
14	Dofequidar	10	24	− 0.44	Investigational	[102]
15	Deferiprone	0.04	24	− 0.44	Approved	[66, 67]
16	Sapitinib	10	24	− 0.44	Investigational	[85]
17	Calcitriol	0.04	24	− 0.44	Approved	[103]
18	PD-153035	0.04	24	− 0.43	Investigational	[104]
19	Finasteride	10	24	− 0.43	Approved	[105]
20	Etofylline-Clofibrate	10	24	− 0.43	Approved

ISSN: 1471-2105