From: Computationally repurposing drugs for breast cancer subtypes using a network-based approach
Rank | Drug | Dosage (μm) | Treatment time (h) | Score | Drug type | References |
---|---|---|---|---|---|---|
1 | Bromocriptine | 0.04 | 24 | − 1 | Approved | [63] |
2 | Ruxolitinib | 10 | 24 | − 0.83 | Approved | |
3 | Fingolimod | 0.04 | 24 | − 0.74 | Approved | [82] |
4 | Tranilast | 0.04 | 24 | − 0.72 | Investigational | [68] |
5 | Etofylline-Clofibrate | 10 | 24 | − 0.71 | Approved |  |
6 | SDZ-NKT-343 | 10 | 24 | − 0.71 | Experimental |  |
7 | Isbufylline | 0.04 | 24 | − 0.71 | Experimental |  |
8 | Raloxifene | 0.04 | 24 | − 0.7 | Approved | [99] |
9 | PHA-767491 | 10 | 24 | − 0.69 | Experimental | [83] |
10 | PF-04217903 | 0.04 | 24 | − 0.69 | Investigational |  |
11 | TG-100801 | 0.04 | 24 | − 0.69 | Investigational |  |
12 | L-690330 | 10 | 24 | − 0.69 | Investigational |  |
13 | MK-1775 | 10 | 24 | − 0.68 | Investigational | |
14 | ICI-185,282 | 0.04 | 24 | − 0.68 | Experimental |  |
15 | Rupatadine | 0.04 | 24 | − 0.67 | Approved |  |
16 | Hymecromone | 0.04 | 24 | − 0.66 | Investigational | [84] |
17 | PD-173074 | 10 | 24 | − 0.66 | Experimental | [88] |
18 | MG-132 | 20 | 24 | − 0.66 | Experimental | [111] |
19 | Raclopride | 10 | 24 | − 0.65 | Investigational |  |
20 | Deferiprone | 0.04 | 24 | − 0.65 | Approved |