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Table 8 Top 20 drugs corresponding to subtype 7

From: Computationally repurposing drugs for breast cancer subtypes using a network-based approach

Rank

Drug

Dosage (μm)

Treatment time (h)

Score

Drug type

References

1

Bromocriptine

0.04

24

− 1

Approved

[63]

2

Ruxolitinib

10

24

− 0.83

Approved

[51, 52]

3

Fingolimod

0.04

24

− 0.74

Approved

[82]

4

Tranilast

0.04

24

− 0.72

Investigational

[68]

5

Etofylline-Clofibrate

10

24

− 0.71

Approved

 

6

SDZ-NKT-343

10

24

− 0.71

Experimental

 

7

Isbufylline

0.04

24

− 0.71

Experimental

 

8

Raloxifene

0.04

24

− 0.7

Approved

[99]

9

PHA-767491

10

24

− 0.69

Experimental

[83]

10

PF-04217903

0.04

24

− 0.69

Investigational

 

11

TG-100801

0.04

24

− 0.69

Investigational

 

12

L-690330

10

24

− 0.69

Investigational

 

13

MK-1775

10

24

− 0.68

Investigational

[109, 110]

14

ICI-185,282

0.04

24

− 0.68

Experimental

 

15

Rupatadine

0.04

24

− 0.67

Approved

 

16

Hymecromone

0.04

24

− 0.66

Investigational

[84]

17

PD-173074

10

24

− 0.66

Experimental

[88]

18

MG-132

20

24

− 0.66

Experimental

[111]

19

Raclopride

10

24

− 0.65

Investigational

 

20

Deferiprone

0.04

24

− 0.65

Approved

[66, 67]