Fig. 10
From: De novo identification of maximally deregulated subnetworks based on multi-omics data with DeRegNet
Consistent upregulation of SYK signaling components and downstream targets in subgraph of patients with poor survival. Inner node color represents the average \(\hbox {log}_2\) fold change across the “SYK-positive” patients and node rim color represent average log2 fold change across the rest of the TCGA-LIHC cohort. Color of edges indicates following interactions: activation (red), inhibition (dark blue), compound (brown), indirect effect (dark grey) and expression (blue green)