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Table 4 The inferred TAD boundaries boundary tagged ratio for 10 functional elements over normalized interaction dataset from human embryonic stem cell line at 5kb resolution

From: A comparison of topologically associating domain callers over mammals at high resolution

 

H3K9me3

H3K4me3

H3K36me3

CTCF

HK genes

TSS

SMC3

SINE

RAD21

Polymerase II

Rank

Armatus

0.695

0.311

0.351

0.630

0.156

0.860

0.570

0.998

0.530

0.501

18

Arrowhead

0.910

0.442

0.512

0.747

0.229

0.911

0.832

0.999

0.796

0.647

32

CaTCH

0.484

0.303

0.341

0.398

0.166

0.488

0.448

0.569

0.429

0.417

9

Constrained HAC

0.910

0.469

0.550

0.737

0.248

0.887

0.856

0.987

0.826

0.672

34

CHDF

0.733

0.338

0.383

0.647

0.161

0.849

0.624

0.978

0.590

0.513

20

ClusterTAD

0.779

0.471

0.533

0.689

0.243

0.807

0.712

0.981

0.691

0.679

29

deDoc

0.858

0.435

0.499

0.724

0.218

0.876

0.788

0.996

0.760

0.636

32

DI

0.920

0.530

0.598

0.747

0.289

0.909

0.858

0.996

0.828

0.733

36

EAST

0.821

0.404

0.476

0.707

0.200

0.880

0.728

0.992

0.694

0.610

27

GMAP

0.848

0.416

0.482

0.699

0.214

0.883

0.740

0.996

0.704

0.628

30

GRiNCH

0.849

0.419

0.485

0.702

0.216

0.884

0.745

0.998

0.705

0.626

30

HiCExplorer

0.942

0.490

0.559

0.770

0.257

0.906

0.894

0.997

0.870

0.698

36

HiCKey

0.944

0.492

0.561

0.768

0.259

0.908

0.894

0.997

0.870

0.699

36

HiCseg

0.872

0.505

0.576

0.706

0.278

0.870

0.804

0.988

0.771

0.705

36

IC-Finder

0.890

0.476

0.535

0.739

0.239

0.902

0.819

0.999

0.789

0.669

35

InsulationScore

0.828

0.430

0.485

0.681

0.208

0.881

0.719

0.971

0.678

0.640

29

Matryoshka

0.740

0.358

0.403

0.639

0.185

0.873

0.628

0.997

0.590

0.544

22

MrTADFinder

0.702

0.294

0.348

0.704

0.130

0.857

0.567

0.998

0.529

0.508

18

MSTD

0.853

0.380

0.450

0.689

0.194

0.872

0.766

0.991

0.726

0.609

27

OnTAD

0.926

0.507

0.577

0.758

0.263

0.910

0.867

0.998

0.841

0.712

36

Spectral

0.665

0.305

0.361

0.649

0.131

0.786

0.548

0.920

0.514

0.477

15

SpectralTAD

0.834

0.399

0.464

0.703

0.200

0.881

0.754

0.998

0.721

0.601

27

TADBD

0.864

0.436

0.499

0.712

0.216

0.901

0.770

0.999

0.737

0.630

30

TADbit

0.912

0.530

0.596

0.763

0.276

0.916

0.844

0.998

0.814

0.731

36

TADpole

0.807

0.421

0.471

0.717

0.205

0.885

0.704

0.998

0.673

0.604

28

TADtree

0.805

0.419

0.470

0.716

0.204

0.883

0.703

0.998

0.671

0.600

28

TopDom

0.897

0.471

0.534

0.730

0.242

0.881

0.841

0.996

0.817

0.674

34

  1. Bold numbers show the leading result for every column. The final column is sum of each caller’s ranking in terms of the whole set of functional regulatory elements except H3K9me3