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Table 6 The mean peak near inferred TAD boundaries (2kb) for six functional elements for both with and without corner dot using the normalized Micro-C dataset over mouse ESCs at a lower 1kb resolution

From: A comparison of topologically associating domain callers over mammals at high resolution

 

H3K9me3

H3K4me3

H3K36me3

RAD21

SMC3

CTCF

H3K9me3

H3K4me3

H3K36me3

RAD21

SMC3

CTCF

With corner dot (extrusion loop)

Without corner dot

Armatus

0.451

0.342

0.353

0.531

0.535

0.565

0.221

0.112

0.123

0.301

0.305

0.335

Arrowhead

0.531

0.392

0.409

0.599

0.617

0.356

0.301

0.162

0.179

0.369

0.387

0.426

CaTCH

0.428

0.324

0.339

0.569

0.597

0.436

0.198

0.094

0.109

0.339

0.367

0.206

Constrained HAC

0.595

0.441

0.468

0.649

0.712

0.574

0.365

0.211

0.238

0.419

0.482

0.344

CHDF

0.578

0.367

0.379

0.537

0.551

0.585

0.248

0.137

0.149

0.307

0.321

0.355

ClusterTAD

0.519

0.385

0.401

0.669

0.703

0.561

0.289

0.155

0.171

0.439

0.473

0.331

deDoc

0.543

0.411

0.427

0.599

0.612

0.614

0.313

0.181

0.197

0.369

0.382

0.384

DI

0.573

0.414

0.436

0.731

0.756

0.581

0.343

0.184

0.206

0.501

0.536

0.351

EAST

0.456

0.351

0.361

0.562

0.586

0.652

0.226

0.121

0.131

0.332

0.356

0.422

GMAP

0.485

0.358

0.372

0.551

0.609

0.611

0.255

0.128

0.142

0.321

0.379

0.381

GRiNCH

0.495

0.362

0.375

0.557

0.614

0.615

0.252

0.129

0.144

0.324

0.381

0.382

HiCExplorer

0.571

0.434

0.476

0.664

0.659

0.615

0.361

0.204

0.236

0.434

0.429

0.385

HiCKey

0.531

0.377

0.399

0.675

0.705

0.548

0.301

0.147

0.171

0.445

0.475

0.317

HiCseg

0.528

0.376

0.398

0.672

0.702

0.545

0.298

0.146

0.168

0.442

0.472

0.315

IC-Finder

0.539

0.398

0.416

0.658

0.656

0.628

0.309

0.168

0.186

0.428

0.426

0.398

InsulationScore

0.473

0.363

0.374

0.564

0.574

0.575

0.243

0.133

0.144

0.334

0.344

0.345

Matryoshka

0.472

0.356

0.371

0.586

0.588

0.563

0.242

0.126

0.141

0.356

0.358

0.333

MrTADFinder

0.413

0.314

0.324

0.446

0.467

0.627

0.183

0.084

0.095

0.236

0.237

0.397

MSTD

0.487

0.357

0.378

0.539

0.556

0.578

0.257

0.127

0.158

0.309

0.336

0.348

OnTAD

0.575

0.429

0.448

0.683

0.677

0.618

0.345

0.199

0.218

0.453

0.447

0.388

Spectral

0.389

0.307

0.316

0.445

0.447

0.617

0.159

0.077

0.086

0.215

0.217

0.387

SpectralTAD

0.509

0.387

0.406

0.582

0.609

0.624

0.279

0.157

0.176

0.352

0.379

0.394

TADBD

0.492

0.372

0.384

0.573

0.585

0.654

0.262

0.142

0.154

0.344

0.355

0.424

TADbit

0.559

0.398

0.422

0.718

0.755

0.608

0.329

0.168

0.192

0.488

0.546

0.378

TADpole

0.483

0.367

0.376

0.596

0.594

0.653

0.351

0.137

0.144

0.365

0.360

0.419

TADtree

0.482

0.365

0.375

0.594

0.592

0.651

0.352

0.135

0.145

0.364

0.362

0.421

TopDom

0.485

0.432

0.457

0.665

0.656

0.585

0.255

0.202

0.227

0.435

0.426

0.355

  1. Bold numbers show the leading result for every column