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Table 2 Empirical type I errors (\(\times 0.05\)) of the TCRL (TCRL-B62 and TCRL-P250) and alternative methods for binary or continuous outcomes

From: TCR-L: an analysis tool for evaluating the association between the T-cell receptor repertoire and clinical phenotypes

Approach

Binary trait

Continuous trait

\(n=350\)

\(n=400\)

\(n=450\)

\(n=350\)

\(n=400\)

\(n=450\)

Ext. features

1.118

1.050

1.008

1.022

1.042

0.956

Seq.-B62

0.980

0.988

0.958

0.938

0.922

0.916

Seq.-P250

0.934

0.944

0.964

0.908

0.890

0.920

TCRL-B62

1.056

1.030

1.050

1.040

1.052

0.980

TCRL-P250

1.014

1.034

1.066

1.028

1.008

0.932