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Table 5 Power comparison of the TCRL and alternative methods for binary or continuous outcomes when only the random effect was considered (S was based on PAM250)

From: TCR-L: an analysis tool for evaluating the association between the T-cell receptor repertoire and clinical phenotypes

Approach

Binary trait

Continuous trait

\(n=350\)

\(n=400\)

\(n=450\)

\(n=350\)

\(n=400\)

\(n=450\)

Ext.features

0.123

0.119

0.127

0.099

0.121

0.107

Seq.-B62

0.804

0.881

0.919

0.778

0.861

0.908

Seq.-P250

0.866

0.929

0.962

0.866

0.917

0.949

TCRL-B62

0.765

0.851

0.886

0.744

0.824

0.860

TCRL-P250

0.824

0.907

0.936

0.816

0.890

0.926