Fig. 2
From: Evaluation of statistical approaches for association testing in noisy drug screening data
The analytical null accurately computes exact p values for CI. a The analytical distribution matches a permutation null of K = 1e6 samples of length 100 from a standard normal distribution. As CI is entirely non-parametric, the choice of distribution is irrelevant. b The Q-Q plot shows the -\(\log\)10 empirical rank of the CI on the x-axis and the -\(\log\)10 theoretical quantile from the analytical null (red) and asymptotic null (blue). The analytical p-values are both monotonic and correctly approximate the uniform distribution (grey)