BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

BMC Bioinformatics

Table 3 NPs, EPs and DPs (in \(\%\)) for the PF and Fieller’s methods

Trait	n	MAF	\({\rho }\)	PF			Fieller
Trait	n	MAF	\({\rho }\)	NP	EP	DP	NP	EP	DP
Qualitative	500	0.3	0	23.4	0.4	0.0	31.4	0.6	0.2
			− 0.05	23.6	0.4	0.0	34.6	0.8	0.0
			0.05	22.6	0.0	0.0	29.4	0.6	0.0
		0.1	0	43.2	1.6	0.0	60.2	0.2	1.0
			− 0.05	47.6	3.6	0.0	54.8	0.0	1.0
			0.05	41.0	1.4	0.0	61.0	0.8	0.4
	2000	0.3	0	0.2	0.0	0.0	0.6	0.2	0.0
			− 0.05	0.4	0.0	0.0	0.6	0.0	0.0
			0.05	0.0	0.0	0.0	0.4	0.2	0.0
		0.1	0	15.8	0.8	0.0	23.8	0.8	0.0
			− 0.05	16.8	3.2	0.0	22.2	1.2	0.6
			0.05	12.8	0.6	0.0	17.0	0.4	0.2
Quantitative	500	0.3	0	3.6	0.2	0.0	5.6	0.6	0.0
			− 0.05	3.6	0.0	0.0	6.2	0.2	0.0
			0.05	3.0	0.0	0.0	5.2	0.2	0.0
		0.1	0	23.2	5.2	0.0	26.2	3.2	0.2
			− 0.05	20.8	5.0	0.0	25.8	2.6	0.6
			0.05	22.0	1.8	0.0	26.8	1.2	0.2
	2000	0.3	0	0.0	0.0	0.0	0.0	0.0	0.0
			− 0.05	0.0	0.4	0.0	0.0	0.4	0.0
			0.05	0.0	0.2	0.0	0.0	0.2	0.0
		0.1	0	3.0	0.2	0.0	4.4	0.6	0.0
			− 0.05	5.8	0.6	0.0	9.0	1.0	0.0
			0.05	2.8	0.4	0.0	5.6	0.6	0.0

Proportions (in \(\%\)) of the noninformative intervals (NP), empty sets (EP) and discontinuous intervals (DP) for the penalized Fieller’s (PF) and Fieller’s methods are given under qualitative trait and quantitative trait with \((\sigma _{0}^{2},\ \sigma _{1}^{2},\ \sigma _{2}^{2})=(1,\ 1.2,\ 1)\)

ISSN: 1471-2105