Table 5 Application to the Graves’ disease data at SNP rs3827440
From: BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation
Stage | Point estimate | \({95\%}\) HPDI or CI | ||||||
|---|---|---|---|---|---|---|---|---|
\({{\hat{\gamma }}_{BN}}\) | \({{\hat{\gamma }}_{BU}}\) | \({{\hat{\gamma }}_{PF}}\) | \({{\hat{\gamma }}_{F}}\) | BN | BU | PF | Fieller | |
GWAS | 0.9835 | 0.9890 | 0.9537 | 0.9567 | (0.2092, 1.6248) | (0.1524, 1.6359) | (0.0241, 1.6441) | [0, 1.6579) |
Replication | 1.4804 | 1.5193 | 1.5120 | 1.5126 | (1.1144, 1.8855) | (1.1274, 1.9064) | (1.1226, 1.9270) | (1.1224, 1.9299) |
Pooled | 1.3693 | 1.3770 | 1.3724 | 1.3727 | (1.0206, 1.7134) | (1.0272, 1.7368) | (1.0280, 1.7184) | (1.0277, 1.7195) |