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Table 6 SNPs detected in association analysis for the MCTFR data

From: BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

SNP

Position

Allele

MAF

P value

Trait

Gene

Minor

Major

HWE test

D-INT

I-INT

O-INT

rs12557060

28772570

G

A

0.4737

0.1781

\(3.883\times 10^{-6}\)

\(4.087\times 10^{-3}\)

\(7.759\times 10^{-6}\)

BD

\(IL1RAPL1^a\)

rs331318

32234387

G

A

0.4847

0.6868

\(5.163\times 10^{-7}\)

\(7.768\times 10^{-4}\)

\(1.032\times 10^{-6}\)

DEP

\(DMD^b\)

rs5928558

34363004

G

A

0.1844

0.0529

\(4.225\times 10^{-6}\)

\(8.921\times 10^{-5}\)

\(8.069\times 10^{-6}\)

DEP

 

rs10522027

34558201

A

G

0.1405

0.1642

\(1.490\times 10^{-8}\)

\(3.094\times 10^{-6}\)

\(2.967\times 10^{-8}\)

DEP

\(TMEM47^c\)

rs3008896

39632138

A

G

0.4654

0.7873

\(3.474\times 10^{-6}\)

\(4.060\times 10^{-3}\)

\(6.942\times 10^{-6}\)

BD

 

rs4240042

39748679

G

A

0.3953

0.9627

\(1.208\times 10^{-6}\)

\(1.352\times 10^{-3}\)

\(2.414\times 10^{-6}\)

CON

 

rs5961051

53906442

C

A

0.4216

0.0810

\(3.541\times 10^{-6}\)

\(4.563\times 10^{-3}\)

\(7.077\times 10^{-6}\)

BD

 

rs4489437

124515139

G

A

0.4481

0.9639

\(2.140\times 10^{-7}\)

\(5.599\times 10^{-4}\)

\(4.277\times 10^{-7}\)

BD

 

rs2097322

124523716

A

C

0.4020

0.6416

\(2.369\times 10^{-6}\)

\(2.042\times 10^{-3}\)

\(4.732\times 10^{-6}\)

BD

 

rs463233

149839444

G

A

0.4800

0.5601

\(4.164\times 10^{-6}\)

\(5.817\times 10^{-3}\)

\(8.321\times 10^{-6}\)

BD

 

rs12849233

150564832

A

C

0.3296

0.7611

\(1.360\times 10^{-7}\)

\(2.196\times 10^{-4}\)

\(2.718\times 10^{-7}\)

DEP

\(PASD1^d\)

  1. The significance level of the three association tests (D-INT, I-INT and O-INT) is set to be \(4.408\times 10^{-6}\);
  2. \(^{\rm a}\)This gene is cited by Walker et al. [42];
  3. \(^{\rm b}\)This gene is cited by Miyagoe-Suzuki et al. [43];
  4. \(^{\rm c}\)This gene is cited by Ng et al. [44];
  5. \(^{\rm d}\)This gene is cited by Li et al. [45]