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Table 7 Application of BN, BU, PF and Fieller’s methods for SNPs detected in association analysis

From: BEXCIS: Bayesian methods for estimating the degree of the skewness of X chromosome inactivation

SNP

Point estimate

\({95\%}\) HPDI or CI

\({{\hat{\gamma }}_{BN}}\)

\({{\hat{\gamma }}_{BU}}\)

\({{\hat{\gamma }}_{PF}}\)

\({{\hat{\gamma }}_{F}}\)

BN

BU

PF

Fieller

rs12557060

0.9234

0.9227

0.9303

0.9386

(0.1500, 1.8080)

(0.0872, 1.8216)

[0, 2]

[0, 2]

rs331318

1.2233

1.2198

1.2586

1.2651

(0.5205, 1.9704)

(0.5313, 1.9988)

(0.4235, 2]

(0.4088, 2]

rs5928558

0.9251

0.9119

0.9744

0.9837

(0.3847, 1.8414)

(0.4016, 1.9173)

(0.3452, 2]

(0.3629, 2]

rs10522027

0.7243

0.6869

0.7595

0.7651

(0.2828, 1.6562)

(0.2689, 1.7268)

(0.2937, 1.8982)

(0.3067, 2]

rs3008896

0.5524

0.4300

0.3920

0.3950

(0.0006, 1.3040)

(0, 1.3026)

[0, 1.3264)

[0, 1.3655)

rs4240042

1.0378

1.0244

1.0648

1.0698

(0.3815, 1.8557)

(0.3893, 1.9351)

(0.3326, 2]

(0.3277, 2]

rs5961051

1.1732

1.2490

1.2863

1.3050

(0.4478, 1.9992)

(0.4118, 2)

(0.2700, 2]

(0.2401, 2]

rs4489437

1.5543

1.6712

1.7697

1.7802

(0.9453, 1.9999)

(0.9708, 2)

(0.9175, 2]

(0.9296, 2]

rs2097322

1.6407

1.7820

1.9987

2.0000

(0.8910, 2)

(0.9109, 2)

(0.8958, 2]

(0.9353, 2]

rs463233

0.3859

0.1586

0.1715

0.1728

(0, 1.1054)

(0, 1.0898)

[0, 1.0713)

[0, 1.0847)

rs12849233

0.6330

0.6580

0.6500

0.6525

(0.0551, 1.4351)

(0.0187, 1.4338)

(0.0201, 1.4681)

(0.0099, 1.5358)

  1. BN, Bayesian method with normal prior; BU, Bayesian method with uniform prior; PF, penalized Fieller’s method