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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Gene co-expression network based on part mutual information for gene-to-gene relationship and gene-cancer correlation analysis

Fig. 7

The generation of a PMI correlation change network. The cancer mRNA transcriptome data from databases is split into normal group and groups of 3 cancer stages. The WGCNA and GO enrichment are ran on each group of data separately. For a GO term enriched in all 4 group along a cancer progress, the gene sets from 4 groups are different, they are combined into one gene set. The expression of the combined gene set of a GO term is used for PMI fully calculation, the resulting networks of 4 groups along a cancer progress are combined into one network, which is the PMI correlation change network

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BMC Bioinformatics

ISSN: 1471-2105

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