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Table 4 Median values for the four selected measures for the first artificial dataset, with uncertainties given by the standard deviation (except for the case of SMSR were the standard deviation is orders of magnitude higher than the median value). From these results it is visible that A) The high values of uncertainty discourage focus on optimizing the biclustering method parameters and B) Choosing the right evaluation metric is important, however in most of the biclusters cases they seem to agree for the same “best” configuration. Bold represents the choosen parameters for the next sections

From: Biclustering fMRI time series: a comparative study

Method Configuration VAR MSR SMSR VE
BicPAM Additive version \(0.024 \pm 0.024\) \(0.001 \pm 0.003\) 2.49 \(\mathbf{0} .\mathbf{262} \pm 0.232\)
Constant version \(0.014 \pm 0.026\) \(0.001 \pm 0.002\) 1.96 \(0.434 \pm 0.185\)
Multiplicative \(0.025 \pm 0.024\) \(0.002 \pm 0.005\) 3.07 \(0.461 \pm 0.263\)
Bimax 10 biclusters \(0.004 \pm 0.002\) \(0.001 \pm 0.001\) 0.03 \(0.881 \pm 0.148\)
100 biclusters \(0.006 \pm 0.004\) \(0.003 \pm 0.002\) 0.05 \(0.729 \pm 0.128\)
1000 biclusters \(0.008 \pm 0.008\) \(0.004 \pm 0.004\) 0.06 \(0.706 \pm 0.168\)
10,000 biclusters \(0.008 \pm 0.007\) \(0.004 \pm 0.004\) 0.06 \(\mathbf{0} .\mathbf{695} \pm 0.169\)
100,000 Biclusters \(0.008 \pm 0.007\) \(0.004 \pm 0.004\) 0.06 \(0.695 \pm 0.169\)
CCC Traditional discretization (5 symbols) \(0.189 \pm 0.359\) \(0.017 \pm 0.021\) 0.51 \(\mathbf{0} .\mathbf{288} \pm 0.345\)
Variation between time points (2 Symbols) \(0.596 \pm 0.491\) \(0.067 \pm 0.108\) 0.93 \(0.370 \pm 0.315\)
Variation between time points (3 Symbols) \(0.596 \pm 0.491\) \(0.067 \pm 0.108\) 0.93 \(0.370 \pm 0.315\)
FABIA Standard \(0.579 \pm 0.502\) \(0.006 \pm 0.081\) 0.51 \(\mathbf{0} .\mathbf{079} \pm 0.167\)
Relaxed \(0.946 \pm 0.053\) \(0.881 \pm 0.095\) 3485.60 \(0.787 \pm 0.036\)
Spectral Biclustering log \(0.039 \pm 0.053\) \(0.033 \pm 0.004\) 670.30 \(\mathbf{0} .\mathbf{726} \pm 0.012\)
bistochastization \(0.040 \pm 0.005\) \(0.035 \pm 0.004\) 3232.21 \(0.731 \pm 0.015\)
irrc \(0.040 \pm 0.004\) \(0.035 \pm 0.004\) 1271.71 \(0.726 \pm 0.015\)
XMotifs Discretization with 2 symbols \(0.017 \pm 0.004\) \(0.012 \pm 0.001\) 1168.76 \(0.662 \pm 0.048\)
Discretization with 5 symbols \(0.007 \pm 0.009\) \(0.003 \pm 0.001\) 6.59 \(\mathbf{0} .\mathbf{585} \pm 0.035\)