BMC Bioinformatics

Table 2 FDR at significance level 0.05

From: HIMA2: high-dimensional mediation analysis and its application in epigenome-wide DNA methylation data

	\(\rho =0\)				\(\rho =0.25\)
	\(p=1000\)		\(p=5000\)		\(p=1000\)		\(p=5000\)
Method	\(n=300\)	\(n=600\)	\(n=300\)	\(n=600\)	\(n=300\)	\(n=600\)	\(n=300\)	\(n=600\)
HIMA2	0.0110	0.0030	0.0634	0.0214	0.0094	0.0053	0.0569	0.0202
HIMA	0.0225	0.0149	0.0316	0.0316	0.0244	0.0238	0.0320	0.0301
HDMA	0.2067	0.2553	0.2994	0.3739	0.1880	0.2299	0.2712	0.3678

	\(\rho =0.50\)				\(\rho =0.75\)
	\(p=1000\)		\(p=5000\)		\(p=1000\)		\(p=5000\)
Method	\(n=300\)	\(n=600\)	\(n=300\)	\(n=600\)	\(n=300\)	\(n=600\)	\(n=300\)	\(n=600\)
HIMA2	0.0099	0.0039	0.0351	0.0129	0.0055	0.0026	0.0097	0.0025
HIMA	0.0322	0.0253	0.0339	0.0281	0.0325	0.0232	0.0306	0.0327
HDMA	0.1482	0.1764	0.2533	0.3174	0.0990	0.1211	0.1740	0.1816

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ISSN: 1471-2105

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