Table 4 Summary of selected CpGs with mediation effects subject to FDR < 0.05
CpGs | Chromosome1 | Positiona | Proximal gene targetb | \({\widehat{\alpha }}_{k}(SE)\) | \({\widehat{\beta }}_{k}(SE)\) | \({\widehat{\alpha }}_{k}{\widehat{\beta }}_{k}\) | FDR |
|---|---|---|---|---|---|---|---|
cg26331243 | chr15 | 74,550,946 | CCDC33 | −0.081 (0.016) | 0.084 (0.027) | −0.0067 | 0.0345 |
cg19862839 | chr17 | 59,543,726 | TBX4 | −0.082 (0.024) | 0.059 (0.020) | −0.0049 | 0.0397 |