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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform

Fig. 1

Overview of Open Targets data and generation of newly computed features. Open Targets association evidence network edge weights are annotated for evidence from multiple sources (a). Novel target-disease association features generated from target-target similarity and target-disease matrices compared with factors used in calculation of a user-item matrix (b). Target-disease arrays are generated for each information source and association evidence for known drug status (c)

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