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Table 6 sc-PDB Binding Sites - \(L_{Grad-RAM}\) matching results (Eq. 8) across different window lengths and for the different formulations of the \(L_{Grad-RAM}\), where lower and higher percentage values are associated with lower and higher number of window-based binding pockets where information is being extracted from at least one position across all the DTI pairs, respectively

From: Explainable deep drug–target representations for binding affinity prediction

Window length

GMP-G

GMP-NG

GAP-G

GAP-NG

0

16.51

16.51

16.51

15.08

1

39.14

39.14

39.14

36.93

2

49.37

49.37

49.37

46.89

3

56.92

56.92

56.92

53.99

4

63.33

63.33

63.33

60.53

5

66.85

66.85

66.85

64.44

  1. GMP, global max pooling; GAP, global AVG pooling; G, guided gradients; NG, non guided gradients