Table 2 The result of molecular docking between the selected epitopes and HLA molecules.
From: In silico design of a multi-epitope vaccine against HPV16/18
Identifier | Epitope | HLA molecule | Lowest energy (kcal/mol) |
|---|---|---|---|
E1 | FIVYIIFVY | HLA-A*02:01 | − 1018.2 |
E2 | FLIHTHARF | HLA-A*02:01 | − 768 |
E3 | YIIFVYIPL | HLA-A*02:01 | − 996.8 |
E4 | YTSLIILVL | HLA-A*02:01 | − 836.3 |
E5 | RAHYNIVTF | HLA-A*02:01 | − 975.1 |
E6 | YAWVLVFVY | HLA-A*02:01 | − 1033.7 |
E7 | FVYIPLFLIHTHARF | DRB1*01:01 | − 1162.6 |
E8 | IRPLLLSVSTYTSLI | DRB1*01:01 | − 993.4 |
E9 | RPLLLSVSTYTSLII | DRB1*01:01 | − 993.6 |
E10 | DSTLRLCVQSTHVDI | DRB1*01:01 | − 973.8 |
E11 | AFTVYVFCFLLPMLL | DRB1*01:01 | − 1162.8 |
E12 | DGVNHQHLPARRAEP | DRB1*01:01 | − 750.9 |
E13 | EIDGVNHQHLPARRA | DRB1*01:01 | − 719.3 |
E14 | GVNHQHLPARRAEPQ | DRB1*01:01 | − 828.4 |
E15 | IDGVNHQHLPARRAE | DRB1*01:01 | − 837.3 |