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Table 6 Percentage of AUC improvement after considering drug–drug similarity

From: Does adding the drug–drug similarity to drug–target interaction prediction methods make a noticeable improvement in their efficiency?

 

Percentage improvement (enzyme) (%)

Percentage improvement (ion channels) (%)

Percentage improvement (GPCR) (%)

Percentage improvement (nuclear receptors) (%)

NRLMF

0.56

0.44

3.02

6.62

BLM-NII

0.02

0.68

0

16.66

NetLapRLS

1.29

0.18

1.41

6.6

WNN-GIP

2.72

11.11

6.97

11.55