Table 1 Simulation settings for inter-study variability parameter (\(\sigma\)), number of studies and number of replicates per study
From: Fused inverse-normal method for integrated differential expression analysis of RNA-seq data
Setting | \(\sigma\) | No. of studies | No. of replicates (case, control) | AUC (MIN, IN, FIN) | Std. dev (MIN, IN, FIN) |
|---|---|---|---|---|---|
1 | 0.15 | 3 | (10, 10) (15, 10) (12, 16) | 0.886, 0.920, 0.920 | 0.005, 0.003, 0.003 |
2 | 0.15 | 5 | (10, 10) (15, 10) (12, 16) (14, 12) (20, 20) | 0.953, 0.970, 0.970 | 0.005, < 0.001, 0.001 |
3 | 0.5 | 3 | (10, 10) (15, 10) (12, 16) | 0.950, 0.965, 0.966 | 0.004, 0.005, 0.005 |
4 | 0.5 | 5 | (10, 10) (15, 10) (12, 16) (14, 12) (20, 20) | 0.957, 0.977, 0.977 | 0.005, 0.005, 0.005 |