Skip to main content

Table 3 Top 10 up- and down-regulated differentially expressed genes (DEGs) identified by the fused inverse-normal method

From: Fused inverse-normal method for integrated differential expression analysis of RNA-seq data

DEGs

(Up)

\({N}_{g}\)

Mean

|logFC|

Effect

BH

p-value

DEGs

(Down)

\({N}_{g}\)

Mean

|logFC|

Effect

BH

p-value

EIF4EBP1

10.45

3.33

+++

\(<1.62\times {10}^{-15}\)

SMAD12

11.19

4.32

−−−

\(<1.62\times {10}^{-15}\)

WEE1

10.39

4.04

+++

\(<1.62\times {10}^{-15}\)

RASGRF2

11.10

4.19

−−−

\(<1.62\times {10}^{-15}\)

VIM

10.39

3.68

+++

\(<1.62\times {10}^{-15}\)

DNAJC6

11.07

3.71

−−−

\(<1.62\times {10}^{-15}\)

NUSAP1

10.29

4.67

+++

\(<1.62\times {10}^{-15}\)

SERPINI1

10.99

4.79

−−−

\(<1.62\times {10}^{-15}\)

HJURP

10.24

5.79

+++

\(<1.62\times {10}^{-15}\)

ATP1B1

10.98

3.35

−−−

\(<1.62\times {10}^{-15}\)

KIF4A

10.15

4.48

+++

\(<1.62\times {10}^{-15}\)

ATP8A1

10.91

3.95

−−−

\(<1.62\times {10}^{-15}\)

KIF20A

10.12

5.80

+++

\(<1.62\times {10}^{-15}\)

JAKMIP3

10.91

4.40

−−−

\(<1.62\times {10}^{-15}\)

AURKB

10.09

5.48

+++

\(<1.62\times {10}^{-15}\)

MFSD6

10.90

2.83

−−−

\(<1.62\times {10}^{-15}\)

UBE2C

10.07

5.95

+++

\(<1.62\times {10}^{-15}\)

DCTN1-AS1

10.88

5.33

−−−

\(<1.62\times {10}^{-15}\)

CCNB2

10.04

4.63

+++

\(<1.62\times {10}^{-15}\)

PRKACB

10.85

2.35

−−−

\(<1.62\times {10}^{-15}\)

  1. The DEGs have been sorted based on the value of the statistic \({N}_{g}\) and the mean of absolute value of the \({\mathrm{log}}_{2}FC\) have been reported. Effect signifies the direction of expression of DEGs in the per-study differential analysis. BH p-value: Benjamini Hochberg p-value