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Table 5 Top 10 differentially expressed genes (DEGs) with mismatched direction of expression across datasets identified by the fused inverse-normal method

From: Fused inverse-normal method for integrated differential expression analysis of RNA-seq data

DEGs

\({N}_{g}\)

Mean |logFC|

Effect

BH p-value

CMTM6

7.58

1.30

+−+

\(3.93\times {10}^{-13}\)

RAD51

7.58

2.82

+−+

\(4.03\times {10}^{-13}\)

NOS1AP

− 7.53

1.37

−+−

\(5.73\times {10}^{-13}\)

MSANTD1

− 7.53

1.31

−+−

\(5.92\times {10}^{-13}\)

PGM2

7.52

1.31

+−+

\(6.35\times {10}^{-13}\)

PSD3

− 7.47

1.67

−+−

\(8.63\times {10}^{-13}\)

GPR82

7.43

4.35

+−+

\(1.24\times {10}^{-12}\)

SPTBN4

− 7.31

1.91

−+−

\(2.78\times {10}^{-12}\)

TSPAN6

7.18

2.08

+−+

\(6.86\times {10}^{-12}\)

ARHGEF28

− 7.06

1.23

+−−

\(1.63\times {10}^{-11}\)

  1. The DEGs have been sorted based on the absolute value of the statistic \({N}_{g}\) and the mean of absolute value of the \({\mathrm{log}}_{2}FC\) have been reported. Effect signifies the direction of expression of DEGs in the per-study differential analysis for GSE123892, GSE151352 and TCGA-GBM respectively. BH p-value: Benjamini Hochberg p-value