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Fig. 6 | BMC Bioinformatics

Fig. 6

From: DAGBagM: learning directed acyclic graphs of mixed variables with an application to identify protein biomarkers for treatment response in ovarian cancer

Fig. 6

Ovarian cancer application. A DAG learned from the Retro-ova data. There are 260 nodes (proteins) and 464 inferred edges. The purple module is of particular interest, as it contains a parent node SAMM50 of the treatment response. B Topology and node information for the purple module in A. C, D Boxplots of protein abundance and RNA expression level of SAMM50 and IMMT in the sensitive and resistant/refractory tumors based on Retro-Ova data. The p values are calculated using Student’s t-test

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