Fig. 3

Regulatory effects of the gastric cancer drug -sensitivity and -resistance markers. The regulatory effects of genes indicate \({\varvec{x}}^{st}_{l}{\hat{\beta }}^{st}_{jl}\) and \({\varvec{x}}^{rs}_{l}{\hat{\beta }}^{rs}_{jl}\) for drug sensitive and resistant cell lines, respectively, where \({\hat{\beta }}^{st}_{jl}\) and \({\hat{\beta }}^{rs}_{jl}\) are estimated in drug sensitive and resistant networks in Fig. 2. “Targets” indicates regulatory effect of the identified markers on their target genes and “Regulators” indicates regulatory effect of the genes on the identified markers in drug sensitive and resistant networks (i.e., \(NW^{st}\) and \(NW^{rs}\))