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Table 1 Amino acid composition, proposition, entropy, adjusted entropy and similarity coefficient (SC) at example positions of the PB2 protein sequence alignment

From: Identifying host-specific amino acid signatures for influenza A viruses using an adjusted entropy measure

Attribute Position 1 (n = 2000) Position 2 (n = 2000)
Composition 1600+ Pro, 200 Phe and 200 Asn 1000 Tyr, 500 Phe and 500 Trp
Proportion (Pi) 0.8# Pro, 0.1 Phe and 0.1 Asn 0.5 Tyr, 0.25 Phe and 0.25 Trp
Entropy 0.639 1.040
SC& 0.625 3.605
Adjusted entropy* 1.022 0.288
  1. +The number preceding the amino acid is the observed number of residues for that amino acid
  2. #The number preceding the amino acid is the observed proportion of residues out of 2000 observed for that amino acid
  3. &SC = Similarity Coefficient
  4. *Adj. Entropy = Entropy/SC. See the methods section for a detailed explanation of adjusted entropy and a simple example