Skip to main content
Fig. 4 | BMC Bioinformatics

Fig. 4

From: SCONCE2: jointly inferring single cell copy number profiles and tumor evolutionary distances

Fig. 4

Breakpoint detection accuracy results across methods. Total distance to nearest breakpoint is shown on the y-axis, and \(\omega = \frac{\#\text { inferred breakpoints}}{\#\text { true breakpoints}}\) is shown along the x-axis. Each dot represents one cell, colored by method. Methods with the highest breakpoint detection accuracy cluster near \(\omega = 1\) (vertical red dotted line) and have lowest total breakpoint distance. Each panel corresponds to a simulation set (A-D). In all simulation sets, using the mean, median, and mode have lower total breakpoint distance than independent cell analyses. Furthermore, using the mean results in \(\omega\) values closest to 1, as it is able to infer fractional copy numbers

Back to article page