Fig. 6
From: Deconvolution of tumor composition using partially available DNA methylation data
Application of PRMeth on TCGA dataset. A Relative proportions of seven types of immune cells in BRCA, SKCM, LAML, or THYM. B Shannon index of the four tumors. C–J Kaplan–Meier survival curves for SKCM stratified by abundances of CD8 + T cells (C) and unknown cell type 4 (G), LAML stratified by abundances of NK cells (D) and unknown cell type 3 (H), THYM stratified by abundances of Macrophages (E) and unknown cell type 2 (I), and BRCA stratified by abundances of unknown cell type 3 (F) and unknown cell type 5 (J). Using the surv_cutpoint function in the survminer package of R to divide cancer patients into high- and low-infiltrating groups based on the proportions of specific cell types. p values are obtained by the Log-rank test