Fig. 6
From: Transforming L1000 profiles to RNA-seq-like profiles with deep learning
Bridge plot of dexamethasone signatures created from the predicted RNA-seq like profiles with all 23,614 genes (red) and 20 random signatures (gray) using the CD method. A–C Unweighted walk comparing ranked genes from the signatures with NR3C1 targets downloaded from ChEA (A) and ENCODE (C). B–D Weighted walk comparing the signatures weighted by the absolute value of the differential expression score for each gene, normalized to a value between 0 and 1 from NR3C1 target genes downloaded from ChEA (B) and ENCODE (D)