Method | Performance (%) on unbalanced training set—1:3 | |||
---|---|---|---|---|
Accuracy | Precision | Recall | Specificity | |
DeepPPI | 98.19 ± 0.58 | 98.73 ± 0.40 | 93.98 ± 2.43 | 99.59 ± 0.13 |
DeepFE-PPI | 98.96 ± 0.27 | 98.30 ± 0.46 | 97.52 ± 0.88 | 99.44 ± 0.15 |
Struct2Graph | 99.30 ± 0.22 | 99.17 ± 0.44 | 98.19 ± 1.09 | 99.71 ± 0.13 |
Method | MCC | F1-score | ROC-AUC | NPV |
---|---|---|---|---|
DeepPPI | 95.15 ± 1.55 | 96.28 ± 1.24 | 99.27 ± 0.14 | 98.03 ± 0.78 |
DeepFE-PPI | 97.21 ± 0.72 | 97.90 ± 0.55 | 99.51 ± 0.11 | 99.18 ± 0.29 |
Struct2Graph | 98.20 ± 0.56 | 98.67 ± 0.41 | 99.49 ± 0.21 | 99.33 ± 0.38 |