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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Atlas of regulated target genes of transcription factors (ART-TF) in human ES cells

Fig. 2

Comparison of methods for delineating regulated target genes of transcription factors (TFs). A, B Counts of direct regulated target genes (total upregulated, downregulated, promoter- and enhancer-dependent) identified by 3 methods described in “Comparison of methods for delineating regulated target genes of TFs” section; each point is a single TF. C Number of TFs that had a reduced or increased counts of direct regulated target genes identified with methods #2 and #3 versus #1. D Probability distribution of z-values (hypergeometric test) that represent the significance of overlap between direct regulated targets identified from different ChIP-seq experiments for the same TF (blue) and between direct and indirect regulated targets for the same set of TF (orange)

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